887256-40-8

887256-40-8 structure

Name: Mesalamine impurity P
Chemical Name: 5-Amino-2-hydroxy-4'-sulfo-3-biphenylcarboxylic acid
CAS Number: 887256-40-8
Molecular Formula: C₁₃H₁₁NO₆S
Molecular Weight: 309.294
Catalog: Signaling Pathways Cell Cycle/DNA Damage PAK
Create Date: 2018-06-02 14:35:30
Modify Date: 2024-01-09 11:23:40
Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1].

Name	5-Amino-2-hydroxy-4'-sulfo-3-biphenylcarboxylic acid
Synonyms	5-Amino-2-hydroxy-4'-sulfo-3-biphenylcarboxylic acid [1,1'-Biphenyl]-3-carboxylic acid, 5-amino-2-hydroxy-4'-sulfo- Mesalazine Impurity 16

Description	Mesalamine impurity P is an impurity of Mesalamine (HY-15027). 5-Aminosalicylic acid (Mesalamine) acts as a specific PPARγ agonist and also inhibits p21-activated kinase 1 (PAK1) and NF-κB[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> PAK Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Inflammation/Immunology Signaling Pathways >> Cell Cycle/DNA Damage >> PAK
Target	PPAR PAK1 NF-κB
References	[1]. Kyle Dammann, et al.PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation.Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2349-60.