Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GBT440
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: GBT-440(Voxelotor)
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: GBT-440(Voxelotor)
Price: $500.0/100mg $800.0/250mg $1600.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Voxelotor
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

1446321-46-5

1446321-46-5 structure

1446321-46-5 structure

Name: GBT-440
Chemical Name: voxelotor
CAS Number: 1446321-46-5
Molecular Formula: C₁₉H₁₉N₃O₃
Molecular Weight: 337.372
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-05-20 08:00:00
Modify Date: 2025-08-23 09:36:34
GBT 440 (Voxelotor) is an orally bioavailable modulator of sickle cell hemoglobin.

Name	voxelotor
Synonyms	Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]- 2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde voxelotor GBT-440 GBT 440

Description	GBT 440 (Voxelotor) is an orally bioavailable modulator of sickle cell hemoglobin.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease
References	[1]. Metcalf B, et al. Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin. ACS Med Chem Lett. 2017 Jan 23;8(3):321-326.

Density	1.2±0.1 g/cm3
Boiling Point	539.2±50.0 °C at 760 mmHg
Molecular Formula	C₁₉H₁₉N₃O₃
Molecular Weight	337.372
Flash Point	279.9±30.1 °C
Exact Mass	337.142639
LogP	2.85
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.617
Storage condition	-20℃

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