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1243685-62-2

1243685-62-2 structure
1243685-62-2 structure
  • Name: SPI-112Me
  • Chemical Name: SPI-112Me
  • CAS Number: 1243685-62-2
  • Molecular Formula: C23H19FN4O5S
  • Molecular Weight: 482.484
  • Create Date: 2018-05-21 08:00:00
  • Modify Date: 2024-09-07 14:28:29
  • SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays.

Name SPI-112Me
Synonyms Benzoic acid, 3-[(2Z)-2-[5-[[[(4-fluorophenyl)methyl]amino]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazinyl]-, methyl ester
Methyl 3-[(2Z)-2-{5-[(4-fluorobenzyl)sulfamoyl]-2-oxo-1,2-dihydro-3H-indol-3-ylidene}hydrazino]benzoate
Density 1.5±0.1 g/cm3
Molecular Formula C23H19FN4O5S
Molecular Weight 482.484
Exact Mass 482.106018
LogP 3.86
Index of Refraction 1.667
Storage condition -20℃
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