1243685-62-2
1243685-62-2 structure
- Name: SPI-112Me
- Chemical Name: SPI-112Me
- CAS Number: 1243685-62-2
- Molecular Formula: C23H19FN4O5S
- Molecular Weight: 482.484
- Create Date: 2018-05-21 08:00:00
- Modify Date: 2025-08-24 22:51:16
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SPI-112Me is a prodrug for SPI-112, which preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by a factor of 20 in cell-free assays.
| Name | SPI-112Me |
|---|---|
| Synonyms |
Benzoic acid, 3-[(2Z)-2-[5-[[[(4-fluorophenyl)methyl]amino]sulfonyl]-1,2-dihydro-2-oxo-3H-indol-3-ylidene]hydrazinyl]-, methyl ester
Methyl 3-[(2Z)-2-{5-[(4-fluorobenzyl)sulfamoyl]-2-oxo-1,2-dihydro-3H-indol-3-ylidene}hydrazino]benzoate |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H19FN4O5S |
| Molecular Weight | 482.484 |
| Exact Mass | 482.106018 |
| LogP | 3.86 |
| Index of Refraction | 1.667 |
| Storage condition | -20℃ |