1033040-23-1

1033040-23-1 structure

Name: TPO agonist 1
Chemical Name: TPO agonist 1
CAS Number: 1033040-23-1
Molecular Formula: C₂₅H₂₂N₈O₂
Molecular Weight: 466.495
Catalog: Signaling Pathways Immunology/Inflammation Thrombopoietin Receptor
Create Date: 2018-04-24 06:08:22
Modify Date: 2024-01-10 09:23:23
TPO agonist 1 can increase production of platelets by stimulating the TPO receptor in people with chronic ITP. (Idiopathic Thrombocytopenic Purpura)target: TPO receptor agonist1、TPO receptor agonists can be also used in Bone marrow fibrosis2、TPOreceptor agonists can decrease bleeding events and reduced need for adjunctive or rescue treatments.

Name	TPO agonist 1
Synonyms	1H-Pyrazole-4,5-dione, 1-(3,4-dimethylphenyl)-3-methyl-, 4-[2-[2-hydroxy-3'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]hydrazone], (4E)- (4E)-2-(3,4-Dimethylphenyl)-4-{[2-hydroxy-3'-(2H-tetrazol-5-yl)-3-biphenylyl]hydrazono}-5-methyl-2,4-dihydro-3H-pyrazol-3-one

Description	TPO agonist 1 can increase production of platelets by stimulating the TPO receptor in people with chronic ITP. (Idiopathic Thrombocytopenic Purpura)target: TPO receptor agonist1、TPO receptor agonists can be also used in Bone marrow fibrosis2、TPOreceptor agonists can decrease bleeding events and reduced need for adjunctive or rescue treatments.
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Thrombopoietin Receptor Research Areas >> Cardiovascular Disease
References	[1]. Zeng Y et al. TPO receptor agonist for chronic idiopathic thrombocytopenic purpura. Cochrane Database Syst Rev. 2011 Jul 6;(7):CD008235. [2]. Siegal D et al. Thrombopoietin receptor agonists in primary immune thrombocytopenia. et al. Semin Hematol. 2013 Jan;50 Suppl 1:S18-21