1399840-35-7
1399840-35-7 structure
- Name: MTDIA
- Chemical Name: MT-DADMe-ImmA
- CAS Number: 1399840-35-7
- Molecular Formula:
- Molecular Weight:
- Create Date: 2018-05-03 15:34:02
- Modify Date: 2025-08-20 08:06:34
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MTDIA, also known as MT-DADMe-ImmA, and Methylthio-DADMe-Immucillin A, is a MTAP inhibitor. Human 5'-methylthioadenosine phosphorylase (MTAP) is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer candidates. TS analogues of MTAP incorporate a cationic nitrogen and a protonated 9-deazaadenine leaving group, which are mimics of the ribocation transition state. MT-ImmA and MT-DADMe-ImmA are two examples of these TS analogues.
| Name | MT-DADMe-ImmA |
|---|---|
| Synonyms | MTDIA HCl |
| No Any Chemical & Physical Properties |