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918407-35-9

918407-35-9 structure
918407-35-9 structure
  • Name: Avoralstat
  • Chemical Name: AVORALSTAT
  • CAS Number: 918407-35-9
  • Molecular Formula: C28H27N5O5
  • Molecular Weight: 513.544
  • Catalog: Research Areas Others
  • Create Date: 2018-07-03 11:43:20
  • Modify Date: 2024-01-21 13:36:00
  • Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema.

Name AVORALSTAT
Synonyms 3-{2-[(4-Carbamimidoylphenyl)carbamoyl]-5-methoxy-4-vinylphenyl}-6-[(cyclopropylmethyl)carbamoyl]-2-pyridinecarboxylic acid
UNII-UX17773O15
AVORALSTAT
2-Pyridinecarboxylic acid, 3-[2-[[[4-[(Z)-aminoiminomethyl]phenyl]amino]carbonyl]-4-ethenyl-5-methoxyphenyl]-6-[[(cyclopropylmethyl)amino]carbonyl]-
Description Avoralstat is an oral plasma kallikrein (PKK) inhibitor, used for the treatment of hereditary angioedema.
Related Catalog
References

[1]. Aygoren-Pursun E, et al. Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat. J Allergy Clin Immunol. 2016 Sep;138(3):934-936.e5.

Density 1.4±0.1 g/cm3
Molecular Formula C28H27N5O5
Molecular Weight 513.544
Exact Mass 513.201233
LogP 0.80
Index of Refraction 1.673