1346528-06-0

1346528-06-0 structure

Name: ML-241
Chemical Name: N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine
CAS Number: 1346528-06-0
Molecular Formula: C₂₃H₂₄N₄O
Molecular Weight: 372.46
Catalog: Signaling Pathways Cell Cycle/DNA Damage p97
Create Date: 2018-02-20 18:40:23
Modify Date: 2024-01-29 18:26:24
ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC50 of 0.11 μM. ML241 can be used for the research of cancer[1].

Name	N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine
Synonyms	N-Benzyl-2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-4-quinazolinamine 4-Quinazolinamine, 2-(2,3-dihydro-4H-1,4-benzoxazin-4-yl)-5,6,7,8-tetrahydro-N-(phenylmethyl)- ML-241

Description	ML241 is a potent, selective and competitive p97 ATPase inhibitor with an IC50 of 0.11 μM. ML241 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> p97
Target	IC50: 0.11 μM (p97 ATPase)[1] Ki: 0.35 μM (p97 ATPase)[1]
References	[1]. Chou TF, et al. Structure-activity relationship study reveals ML240 and ML241 as potent and selective inhibitors of p97 ATPase. ChemMedChem. 2013 Feb;8(2):297-312.