1204918-72-8
1204918-72-8 structure
- Name: SB-1317
- Chemical Name: (16E)-14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene
- CAS Number: 1204918-72-8
- Molecular Formula: C23H24N4O
- Molecular Weight: 372.46
- Catalog: Signaling Pathways Cell Cycle/DNA Damage CDK
- Create Date: 2018-06-04 03:07:15
- Modify Date: 2024-01-13 11:30:04
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Zotiraciclib (TG02) is an orally active potent inhibitor of CDK2, JAK2 and FLT3 with IC50 values of 13, 73, and 56 nM, respectively. Zotiraciclib can be used for the research of advanced leukemias and multiple myeloma[1][2].
| Name | (16E)-14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene |
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| Synonyms |
(16E)-14-Methyl-20-oxa-5,7,14,27-tetraazatetracyclo[19.3.1.1.1]heptacosa-1(25),2(27),3,5,8(26),9,11,16,21,23-decaene
20-Oxa-5,7,14,27-tetraazatetracyclo[19.3.1.1.1]heptacosa-1(25),2,4,6(27),8,10,12(26),16,21,23-decaene, 14-methyl-, (16E)- SB-1317 |
| Description | Zotiraciclib (TG02) is an orally active potent inhibitor of CDK2, JAK2 and FLT3 with IC50 values of 13, 73, and 56 nM, respectively. Zotiraciclib can be used for the research of advanced leukemias and multiple myeloma[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 577.1±60.0 °C at 760 mmHg |
| Molecular Formula | C23H24N4O |
| Molecular Weight | 372.46 |
| Flash Point | 302.8±32.9 °C |
| Exact Mass | 372.195007 |
| LogP | 4.76 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.577 |