1125780-41-7
1125780-41-7 structure
- Name: SKLB 610
- Chemical Name: N-Methyl-4-(4-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)-2-pyridinecarboxamide
- CAS Number: 1125780-41-7
- Molecular Formula: C21H16F3N3O3
- Molecular Weight: 415.365
- Create Date: 2018-12-03 19:05:40
- Modify Date: 2025-09-10 06:57:53
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SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2 and PDGFR at rate of 97%, 65% and 55%, respectively, at concentration of 10 μM in biochemical kinase assays.
| Name | N-Methyl-4-(4-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)-2-pyridinecarboxamide |
|---|---|
| Synonyms |
2-Pyridinecarboxamide, N-methyl-4-[4-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]-
N-Methyl-4-(4-{[3-(trifluoromethyl)benzoyl]amino}phenoxy)-2-pyridinecarboxamide SKLB 610 SKLB610 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 500.9±50.0 °C at 760 mmHg |
| Molecular Formula | C21H16F3N3O3 |
| Molecular Weight | 415.365 |
| Flash Point | 256.8±30.1 °C |
| Exact Mass | 415.114380 |
| LogP | 3.49 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.595 |
| Storage condition | -20℃ |