- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Lusutrombopag
- Price: ￥1656.0/100mg ￥2636.0/250mg ￥1106.0/50mg ￥746.0/25mg
- Purity: 97.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Lusutrombopag（S-888711）
- Price: $600.0/50mg $1000.0/100mg $1700.0/250mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Lusutrombopag
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Lusutrombopag
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
1110766-97-6
1110766-97-6 structure
- Name: Lusutrombopag
- Chemical Name: Lusutrombopag
- CAS Number: 1110766-97-6
- Molecular Formula: C29H32Cl2N2O5S
- Molecular Weight: 591.546
- Catalog: Signaling Pathways Immunology/Inflammation Thrombopoietin Receptor
- Create Date: 2018-08-19 15:12:14
- Modify Date: 2024-01-02 15:05:09
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Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
| Name | Lusutrombopag |
|---|---|
| Synonyms |
S-888711
Acide (2E)-3-{2,6-dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)éthyl]-2-méthoxyphényl}-1,3-thiazol-2-yl)carbamoyl]phényl}-2-méthylacrylique (2E)-3-{2,6-Dichloro-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylacrylic acid 2-Propenoic acid, 3-[2,6-dichloro-4-[[[4-[3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl]-2-thiazolyl]amino]carbonyl]phenyl]-2-methyl-, (2E)- (2E)-3-{2,6-Dichlor-4-[(4-{3-[(1S)-1-(hexyloxy)ethyl]-2-methoxyphenyl}-1,3-thiazol-2-yl)carbamoyl]phenyl}-2-methylacrylsäure |
| Description | Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease. |
|---|---|
| Related Catalog | |
| In Vitro | Lusutrombopag acts selectively on the human TPO receptor and activates signal transduction pathways that promote the proliferation and differentiation of bone marrow cells into megakaryocytes, thereby increasing platelet levels[1]. |
| References |
[1]. Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8. |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C29H32Cl2N2O5S |
| Molecular Weight | 591.546 |
| Exact Mass | 590.140869 |
| LogP | 8.64 |
| Index of Refraction | 1.618 |
| Storage condition | 2-8℃ |