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Product Name: 3-[4-(β-D-Glucopyranosyloxy)phenyl]-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
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154-36-9

154-36-9 structure

Name: Prunetrin
Chemical Name: 3-{4-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]phenyl}-5-hydroxy-7-methoxychromen-4-one
CAS Number: 154-36-9
Molecular Formula: C₂₂H₂₂O₁₀
Molecular Weight: 446.40400
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-06-28 17:00:10
Modify Date: 2025-08-25 14:39:09
Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2].

Name	3-{4-[(2S,4S,5S,3R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)(2H-3,4,5,6-tetrahydropyran-2-yloxy)]phenyl}-5-hydroxy-7-methoxychromen-4-one
Synonyms	3-(4-β-D-glucopyranosyloxy-phenyl)-5-hydroxy-7-methoxy-chromen-4-one 5-Hydroxy-7-methoxy-3-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-phenyl]-chromen-4-one prunetin-4'-O-β-D glucopyranoside prunetrin Prunetin 4'-O-β-D-glucopyranoside prunetin 4'-O-[β-D-glucopyranoside] 4',5-dihydroxy-7-methoxyisoflavone-4'-O-β-D-glucopyranoside

Description	Prunetin (Trifoside), an O-methylated isoflavone found in Prunus yedoensis, possesses anti-inflammatory activities[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	Prunetin inhibits LPS-induced nitric oxide and prostaglandin E2 production through the suppression of iNOS and COX-2 at the transcriptional level[1]. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells[2].
References	[1]. Yang G, et al. Anti-inflammatory effect of prunetin via the suppression of NF-κB pathway. Food Chem Toxicol. 2013;58:124-132. [2]. Hu H, et al. Prunetin inhibits lipopolysaccharide-induced inflammatory cytokine production and MUC5AC expression by inactivating the TLR4/MyD88 pathway in human nasal epithelial cells. Biomed Pharmacother. 2018;106:1469-1477.