774603-04-2
774603-04-2 structure
- Name: 10-Nitrolinoleic acid
- Chemical Name: (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid
- CAS Number: 774603-04-2
- Molecular Formula: C18H31NO4
- Molecular Weight: 325.443
- Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
- Create Date: 2018-04-14 20:21:59
- Modify Date: 2025-08-25 14:07:57
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10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1].
| Name | (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid |
|---|---|
| Synonyms |
(9E,12Z)-10-Nitro-9,12-octadecadienoic acid
9,12-Octadecadienoic acid, 10-nitro-, (9E,12Z)- 10-nitrolinoleic acid |
| Description | 10-Nitrolinoleic acid is a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist. 10-Nitrolinoleic acid competes with [3H]Rosiglitazone for binding to PPAR-γ, with an IC50 of 0.22 μM[1]. |
|---|---|
| Related Catalog | |
| Target |
PPARγ:0.22 μM (IC50) |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 452.2±33.0 °C at 760 mmHg |
| Molecular Formula | C18H31NO4 |
| Molecular Weight | 325.443 |
| Flash Point | 173.9±13.8 °C |
| Exact Mass | 325.225311 |
| PSA | 83.12000 |
| LogP | 6.10 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.493 |
| Storage condition | -20℃ |