23983-05-3

23983-05-3 structure

Name: WT-TTR inhibitor 1
Chemical Name: 2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one
CAS Number: 23983-05-3
Molecular Formula: C₁₆H₉ClN₂OS
Molecular Weight: 312.77
Catalog: Research Areas Neurological Disease
Create Date: 2018-05-17 19:37:05
Modify Date: 2025-09-18 09:03:19
WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].

Name	2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one
Synonyms	2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-benzo[4,5]imidazo[2,1-b]thiazol-3-one

Description	WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].
Related Catalog	Research Areas >> Neurological Disease
References	[1]. Avadhesha Surolia. Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates. Patent US20100190832A1.