59464-18-5

59464-18-5 structure

Name: 2-Thiopseudouridine
Chemical Name: 2-thio-pseudo-U
CAS Number: 59464-18-5
Molecular Formula: C₉H₁₂N₂O₅S
Molecular Weight: 260.27
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-02-28 10:06:43
Modify Date: 2025-09-13 09:39:51
2-Thiopseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-thio-pseudo-U
Synonyms	2-thio-pseudouridine 2-Thiopseudouridin (β-Isomer) 2-thiopseudouridine 5-β-D-ribofuranosyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 5-((2S,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 2-Thiopseudouridin

Description	2-Thiopseudouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.