20931-58-2

20931-58-2 structure

Name: ISOCRYPTOMERIN
Chemical Name: 7''-monomethylhinokiflavone
CAS Number: 20931-58-2
Molecular Formula: C₃₁H₂₀O₁₀
Molecular Weight: 552.48
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-06-08 09:04:11
Modify Date: 2024-02-04 17:17:16
lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities[1][2].

Name	7''-monomethylhinokiflavone
Synonyms	isocryptomerin 6-[4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)-phenoxy]-5-hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chromen-4-one Isocryptomerin isocrtyptomerin 6-[4-(5,7-Dihydroxy-4-oxo-4H-chromen-2-yl)-phenoxy]-5-hydroxy-2-(4-hydroxy-phenyl)-7-methoxy-chromen-4-one

Description	lsocryptomerin is a membrane-active antifungal compound that can be isolated from Selaginella tamariscina. lsocryptomerin can depolarize fungal plasma membrane. lsocryptomerin also shows anticancer and antibacterial activities[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	lsocryptomerin 抑制淋巴细胞增殖，对人肿瘤细胞系具有细胞毒性[1]。 lsocryptomerin (48 h) 具有抗真菌活性，对 C. albicans、T. beigelii 和 S. cerevisiae 的 MIC 值均为 18.11 μM[1]。
References	[1]. Lee J, et al. Isocryptomerin, a novel membrane-active antifungal compound from Selaginella tamariscina. Biochem Biophys Res Commun. 2009 Feb 13;379(3):676-80. [2]. Lee J, et al. Antibacterial and synergistic activity of isocryptomerin isolated from Selaginella tamariscina. J Microbiol Biotechnol. 2009 Feb;19(2):204-7.