50980-32-0

50980-32-0 structure

Name: ankaflavin
Chemical Name: ankaflavin
CAS Number: 50980-32-0
Molecular Formula: C₂₃H₃₀O₅
Molecular Weight: 386.48100
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2018-10-17 20:29:45
Modify Date: 2024-01-05 09:47:11
Ankaflavin, isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells[1][2].

Name	ankaflavin
Synonyms	Ankaflavin (3S,3aR,9aR)-9a-Methyl-3-octanoyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione

Description	Ankaflavin, isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Inflammation/Immunology
Target	PPARγ[2].
References	[1]. Su NW, et al. Ankaflavin from Monascus-fermented red rice exhibits selective cytotoxic effect and induces cell death on Hep G2 cells. J Agric Food Chem. 2005 Mar 23;53(6):1949-54. [2]. Lee BH, et al. Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic Biol Med. 2012 Dec 1;53(11):2008-16.