89845-82-9

89845-82-9 structure

Name: 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
Chemical Name: 2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
CAS Number: 89845-82-9
Molecular Formula: C₁₇H₂₅N₃O₅S
Molecular Weight: 383.46
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-05-05 05:53:21
Modify Date: 2024-02-05 10:46:12
2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2',3'-O-isopropylidene-5-pyrrolidinomethyl-2-thiouridine
Synonyms	1-((3aR,4R,6R,6aR)-6-Hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-5-pyrrolidin-1-ylmethyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one

Description	2',3'-O-Isopropylidene-5-pyrrolidinomethyl-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.