20406-82-0

20406-82-0 structure

Name: 2',3'-O-Isopropylidene 5-hydroxyuridine
Chemical Name: 2',3'-O-isopropylidene-5-hydroxyuridine
CAS Number: 20406-82-0
Molecular Formula: C₁₂H₁₆N₂O₇
Molecular Weight: 300.26
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2018-02-26 23:53:42
Modify Date: 2024-01-16 23:44:04
2’,3’-Isopropylidene-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2',3'-O-isopropylidene-5-hydroxyuridine
Synonyms	5-Hydroxy-2',3'-O-isopropylideneuridine 5-Hydroxy-1-((3aR,4R,6R,6aR)-6-hydroxymethyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1H-pyrimidine-2,4-dione 5-hydroxy-O2',O3'-isopropylidene-uridine 2',3'-O-Isopropyliden-5-hydroxy-uridin

Description	2’,3’-Isopropylidene-5-hydroxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.