86293-41-6

86293-41-6 structure

Name: 10-hydroxycanthin-6-one
Chemical Name: 10-hydroxycanthin-6-one
CAS Number: 86293-41-6
Molecular Formula: C₁₄H₈N₂O₂
Molecular Weight: 236.22600
Catalog: Research Areas Cancer
Create Date: 2017-12-09 16:58:55
Modify Date: 2025-08-27 13:26:28
10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].

Name	10-hydroxycanthin-6-one
Synonyms	10-Hydroxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one 6H-Indolo(3,2,1-de)(1,5)naphthyridin-6-one,10-hydroxy ervine CHEBI:66064

Description	10-Hydroxycanthin-6-one is an antileukemic canthin-6-one alkaloid from Brucea antidysenterica. Antitumor agent[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	10-Hydroxycanthin-6-one shows antibacterial activity with a MIC of 15.62 µg/mL for B. cereus[1].
References	[1]. N Fukamiya, et al. Antitumor agents: LXXXVII. Cytotoxic antileukemic canthin-6-one alkaloids from Brucea antidysenterica and the structure activity relationships of their related derivatives. Planta Med. 1987 Apr;53(2):140-3.