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433694-46-3

433694-46-3 structure
433694-46-3 structure
  • Name: BRD32048
  • Chemical Name: brd32048
  • CAS Number: 433694-46-3
  • Molecular Formula: C16H22N6O
  • Molecular Weight: 314.385
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage DNA/RNA Synthesis
  • Create Date: 2018-02-26 06:50:15
  • Modify Date: 2024-01-14 18:11:40
  • BRD32048 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen[1].

Name brd32048
Synonyms N-(4-Methoxyphenyl)-6-(1-piperidinylmethyl)-1,3,5-triazine-2,4-diamine
1,3,5-Triazine-2,4-diamine, N-(4-methoxyphenyl)-6-(1-piperidinylmethyl)-
Description BRD32048 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen[1].
Related Catalog
References

[1]. Marius S Pop, et al. A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein. Mol Cancer Ther. 2014 Jun;13(6):1492-502.

Density 1.3±0.1 g/cm3
Boiling Point 545.3±60.0 °C at 760 mmHg
Molecular Formula C16H22N6O
Molecular Weight 314.385
Flash Point 283.6±32.9 °C
Exact Mass 314.185516
PSA 89.19000
LogP 1.23
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.650
RIDADR NONH for all modes of transport
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