1134163-29-3

1134163-29-3 structure

Name: Pioglitazone D4
Chemical Name: 5-({4-[2-(5-Ethyl-2-pyridinyl)ethoxy](2H4)phenyl}methyl)-1,3-thiazolidine-2,4-dione
CAS Number: 1134163-29-3
Molecular Formula: C₁₉H₁₆D₄N₂O₃S
Molecular Weight: 360.46300
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2018-04-17 13:28:05
Modify Date: 2025-08-27 13:38:16
Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].

Name	5-({4-[2-(5-Ethyl-2-pyridinyl)ethoxy](2H4)phenyl}methyl)-1,3-thiazolidine-2,4-dione
Synonyms	5-({4-[2-(5-Ethyl-2-pyridinyl)ethoxy](H)phenyl}methyl)-1,3-thiazolidine-2,4-dione 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl-2,3,5,6-d]methyl]-

Description	Pioglitazone D4 (U 72107 D4) is a deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selective PPARγ agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 and 0.99 μM for human and mouse PPARγ, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
References	[1]. Kuwabara K, et al. A novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-c-5-[4-[5-methyl-2-(4-methylphenyl)-4-oxazolyl]butyl]-1,3-dioxane-r-2-carboxylic acid (NS-220), potently decreases plasma triglyceride and glucose leve