1219803-97-0

1219803-97-0 structure
1219803-97-0 structure
  • Name: metolachlor-d6
  • Chemical Name: metolachlor-d6
  • CAS Number: 1219803-97-0
  • Molecular Formula: C15H16ClD6NO2
  • Molecular Weight: 289.831
  • Catalog: Research Areas Others
  • Create Date: 2018-02-16 17:09:58
  • Modify Date: 2024-01-16 12:45:02
  • Metolachlor-d6 is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].

Name metolachlor-d6
Synonyms Acetamide, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-[1-(methoxymethyl-d)ethyl-1,2,2,2-d]-
2-Chloro-N-(2-ethyl-6-methylphenyl)-N-[1-methoxy(H)-2-propanyl]acetamide
2-Chloro-N-(2-ethyl-6-methylphenyl)-N-[1-methoxy(H)propan-2-yl]acetamide
Description Metolachlor-d6 is the deuterium labeled Metolachlor[1]. Metolachlor is a pre-emergent selective, chloroacetanilide herbicide for the control of a variety of annual grass and broad leaf weeds in corn and other crops. Metolachlor is a chiral herbicide consisting of four stereoisomers[2][3].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Jingqian Xie, et al. Metolachlor Stereoisomers: Enantioseparation, Identification and Chiral Stability. J Chromatogr A. 2016 Sep 9;1463:42-8.  

[3]. D M Stamper, et al. Biodegradation of the Acetanilide Herbicides Alachlor, Metolachlor, and Propachlor. Crit Rev Microbiol. 199824(1):1-22.  

Density 1.1±0.1 g/cm3
Boiling Point 406.8±45.0 °C at 760 mmHg
Molecular Formula C15H16ClD6NO2
Molecular Weight 289.831
Flash Point 199.8±28.7 °C
Exact Mass 289.171570
PSA 29.54000
LogP 3.00
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.533
Storage condition -20°C