1429192-00-6

1429192-00-6 structure

Name: Retro-2 cycl
Chemical Name: 2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one
CAS Number: 1429192-00-6
Molecular Formula: C₁₉H₁₆N₂OS
Molecular Weight: 320.41
Catalog: Research Areas Infection
Create Date: 2018-06-29 11:37:15
Modify Date: 2025-08-27 06:53:24
Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively[1]. Antiviral agent[1].

Name	2-(5-methylthiophen-2-yl)-3-phenyl-2,3-dihydroquinazolin-4(1H)-one
Synonyms	rn-1-001

Description	Retro-2 cycl (RN 1-001) is a dihydroquinazolinone (DHQZ) inhibitor of retrograde trafficking. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus with IC50s of 54 μM and 160 μM, respectively[1]. Antiviral agent[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Carney DW, et al. Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses. Bioorg Med Chem. 2014 Sep 1;22(17):4836-47.

RIDADR	NONH for all modes of transport