1061556-49-7
1061556-49-7 structure
- Name: Lei-Dab 7 TFA
- Chemical Name: (Dab7)-Leiurotoxin I
- CAS Number: 1061556-49-7
- Molecular Formula: C141H236N46O39S6
- Molecular Weight: 3394.07
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2016-05-31 01:48:33
- Modify Date: 2025-08-27 11:54:45
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Lei-Dab7 is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.
| Name | (Dab7)-Leiurotoxin I |
|---|
| Description | Lei-Dab7 is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 increases theta-burst responses and increases LTP in rat hippocampal slices in vitro. |
|---|---|
| Related Catalog |
| Molecular Formula | C141H236N46O39S6 |
|---|---|
| Molecular Weight | 3394.07 |