773888-45-2
773888-45-2 structure
- Name: Biotin alkyne
- Chemical Name: N-(Prop-2-ynyl)biotinamide
- CAS Number: 773888-45-2
- Molecular Formula: C13H19N3O2S
- Molecular Weight: 281.37400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-05-12 08:00:00
- Modify Date: 2025-09-21 07:19:00
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Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | N-(Prop-2-ynyl)biotinamide |
|---|---|
| Synonyms |
Biotin propargylamide, 3-(D-Biotinylamido)-1-propyne, Prop-2-ynylamide biotin
5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(prop-2-ynyl)pentanamide |
| Description | Biotin alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.185±0.06 g/cm3(Predicted) |
|---|---|
| Boiling Point | 614.8±50.0 °C(Predicted) |
| Melting Point | 169-170 °C |
| Molecular Formula | C13H19N3O2S |
| Molecular Weight | 281.37400 |
| Exact Mass | 281.12000 |
| PSA | 95.53000 |
| LogP | 1.51010 |
| Hazard Codes | Xi |
|---|