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460-35-5

460-35-5 structure
460-35-5 structure

Name 3-Chloro-1,1,1-trifluoropropane
Synonyms EINECS 207-307-0
3-chloro-1,1,1-trifluoropropane
1,1,1-Trifluoro-3-chloropropane
Propane, 3-chloro-1,1,1-trifluoro-
HCFC-253fb
MFCD00069094
Density 1.3±0.1 g/cm3
Boiling Point 44.1±8.0 °C at 760 mmHg
Melting Point -106.2℃
Molecular Formula C3H4ClF3
Molecular Weight 132.512
Flash Point -6.8±10.4 °C
Exact Mass 131.995361
LogP 1.55
Vapour Pressure 380.2±0.1 mmHg at 25°C
Index of Refraction 1.324

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX6200000
CHEMICAL NAME :
Propane, 3-chloro-1,1,1-trifluoro-
CAS REGISTRY NUMBER :
460-35-5
BEILSTEIN REFERENCE NO. :
1734941
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C3-H4-Cl-F3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
62 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - somnolence (general depressed activity) Behavioral - ataxia
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2300 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1062 mg/kg/30W-I
TOXIC EFFECTS :
Behavioral - alteration of classical conditioning
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1062 mg/kg/30W-I
TOXIC EFFECTS :
Blood - change in clotting factors Blood - other changes
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963
Hazard Codes Xi: Irritant;
Risk Phrases 22-36
Safety Phrases 23-24/25-26
HS Code 2903791090
HS Code 2903791090
Summary 2903791090 halogenated derivatives of methane, ethane or propane (hcfcs)only with fluorine and chlorine。supervision conditions:14xy(import license,export license,export license,export license)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%