157066-76-7
157066-76-7 structure
- Name: SNAP 5089
- Chemical Name: 5-[[[3-(4,4-Diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3-pyridinecarboxylicacidmethylesterhydrochloride
- CAS Number: 157066-76-7
- Molecular Formula: C36H41ClN4O5
- Molecular Weight: 645.18800
- Create Date: 2016-01-27 22:09:14
- Modify Date: 2025-08-28 09:16:53
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SNAP5089 is a subtype-selective α1A-adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (Kivalues are 0.35, 220, 370, 540, 800 and 1200 nM for α1A, α1B, α2C, α1D, α2B and α2A subtypes respectively and 540 nM for L-type Ca2+ channels).
| Name | 5-[[[3-(4,4-Diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-3-pyridinecarboxylicacidmethylesterhydrochloride |
|---|---|
| Synonyms | snap 5089 |
| Molecular Formula | C36H41ClN4O5 |
|---|---|
| Molecular Weight | 645.18800 |
| Exact Mass | 644.27700 |
| PSA | 116.49000 |
| LogP | 7.57380 |