137565-28-7

137565-28-7 structure

Name: [Lys5,MeLeu9,Nle10] -NKA(4-10)
Chemical Name: [Lys5,MeLeu9,Nle10]-NKA(4-10)
CAS Number: 137565-28-7
Molecular Formula: C₃₉H₆₅N₉O₉
Molecular Weight: 803.98800
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2018-06-12 11:04:49
Modify Date: 2025-08-27 00:05:50
[Lys5,MeLeu9,Nle10]-NKA(4-10) is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM[1].

Name	[Lys5,MeLeu9,Nle10]-NKA(4-10)
Synonyms	L-Asp-L-Lys-L-Phe-L-Val-Gly-N-methyl-L-Leu-L-Nle-NH2

Description	[Lys5,MeLeu9,Nle10]-NKA(4-10) is a highly selective and potent NK2 receptor agonist, with an IC50 of 6.1 nM[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
References	[1]. G Chassaing, et al. Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides. 1991 Jun;19(2):91-5. [2]. M A Matuszek, et al. An investigation of tachykinin NK2 receptor subtypes in the rat. Eur J Pharmacol. 1998 Jul 3;352(1):103-9.