123714-50-1

123714-50-1 structure

Name: Acetyl-Calpastatin (184-210) (human) trifluoroacetate salt
Chemical Name: Acetyl-Calpastatin (184-210) (human)
CAS Number: 123714-50-1
Molecular Formula: C₁₄₂H₂₃₀N₃₆O₄₄S
Molecular Weight: 3177.63000
Catalog: Biochemical Peptide
Create Date: 2018-12-03 19:32:52
Modify Date: 2025-08-25 09:00:52
Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively[1][2].

Name	Acetyl-Calpastatin (184-210) (human)

Description	Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversible calpain inhibitor with Ki values of 0.2 nM and 6 μM for µ-calpain and cathepsin L, respectively[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
In Vitro	Acetyl-Calpastatin(184-210)(human) (peptide 1; 12.5-100 μM) inhibits calpains in LCLC 103H cells with an IC50 of 27 μM[1].
References	[1]. Ferdinando Fiorino, et al. A new cell-permeable calpain inhibitor. J Pept Sci. 2007 Jan;13(1):70-3. [2]. Benjamin P Davis, et al. Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment. JCI Insight. 2016 Apr;1(4):e86355.

WGK Germany	3