61278-30-6

61278-30-6 structure

Name: D-Saccharic acid 1,4-lactone hydrate
Chemical Name: (2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid,hydrate
CAS Number: 61278-30-6
Molecular Formula: C₆H₁₀O₈
Molecular Weight: 192.12400
Catalog: Biochemical Carbohydrate Monosaccharide
Create Date: 2018-04-20 08:00:00
Modify Date: 2024-01-09 11:33:40
D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].

Name	(2S)-2-[(3R,4R)-3,4-dihydroxy-5-oxooxolan-2-yl]-2-hydroxyacetic acid,hydrate
Synonyms	D-Saccharolactone D-Saccharic acid 1,4-lactone monohydrate D-Glucaro-1,4-lactone Monohydrate 1,4-Lactone-D-glucaric Acid Monohydrate D-Glucaro-1,4-lacton D-Glucaric acid-1,4-lactone MFCD00149334

Description	D-Saccharic acid 1,4-lactone hydrate is a potent β-glucuronidase inhibitor (IC50=48.4 μM). D-Saccharic acid 1,4-lactone hydrate can be used as a standard drug compared with novel β-glucuronidase inhibitors. D-Saccharic acid 1,4-lactone hydrate possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Taha M, et al. Synthesis, β-glucuronidase inhibition and molecular docking studies of hybrid bisindole-thiosemicarbazides analogs. Bioorg Chem. 2016;68:56-63. [2]. Bhattacharya S, et al. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways. J Biochem Mol Toxicol. 2011;25(6):341-354.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
HS Code	2932190090

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%