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                                    CHEMICAL IDENTIFICATION
 
  RTECS NUMBER :
 
  WW5855000
  
 
  CHEMICAL NAME :
 
  Tantalum oxide
  
 
  CAS REGISTRY NUMBER :
 
  1314-61-0
  
 
  LAST UPDATED :
 
  199712
  
 
  DATA ITEMS CITED :
 
  12
  
 
  MOLECULAR FORMULA :
 
  O5-Ta2
  
 
  MOLECULAR WEIGHT :
 
  441.90
  
 
  WISWESSER LINE NOTATION :
 
  TA2 O5
  HEALTH HAZARD DATAACUTE TOXICITY DATA
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Oral
  
 
  SPECIES OBSERVED :
 
  Rodent - rat
  
 
  DOSE/DURATION :
 
  8 gm/kg
  
 
  TOXIC EFFECTS :
 
  Details of toxic effects not reported other than lethal dose value
  
 
  REFERENCE :
 
  EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep. Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 1,1,1975
  
 
  TYPE OF TEST :
 
  LD - Lethal dose
  
 
  ROUTE OF EXPOSURE :
 
  Intraperitoneal
  
 
  SPECIES OBSERVED :
 
  Rodent - rat
  
 
  DOSE/DURATION :
 
  >5 gm/kg
  
 
  TOXIC EFFECTS :
 
  Vascular - regional or general arteriolar or venous dilation Liver - other changes Blood - other changes
  
 
  REFERENCE :
 
  INMEAF Industrial Medicine. (Chicago, IL) V.1-18, 1932-49. For publisher information, see IOHSA5. Volume(issue)/page/year: 15,482,1946
  
 
  TYPE OF TEST :
 
  LD50 - Lethal dose, 50 percent kill
  
 
  ROUTE OF EXPOSURE :
 
  Oral
  
 
  SPECIES OBSERVED :
 
  Rodent - mouse
  
 
  DOSE/DURATION :
 
  >4 gm/kg
  
 
  TOXIC EFFECTS :
 
  Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - acute pulmonary edema Liver - hepatitis (hepatocellular necrosis), diffuse
  
 
  REFERENCE :
 
  HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA. (Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year: 32(10-12),343,1967 *** REVIEWS *** ACGIH TLV-TWA 5 mg(Ta)/m3, dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 5mg(Ta)/m3, dust DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Gen Indu):8H TWA 5 mg/m3, dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 mg/m3, dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 mg/m3, dust CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 5 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
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