Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: 1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE
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224047-41-0

224047-41-0 structure

Name: (Rac)-Brassinazole
Chemical Name: 4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazol-1-yl)butan-2-ol
CAS Number: 224047-41-0
Molecular Formula: C₁₈H₁₈ClN₃O
Molecular Weight: 327.808
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2018-12-25 12:35:13
Modify Date: 2024-01-03 18:28:52
(Rac)-Brassinazole, triazole-type compound, is a brassinosteroid (BR) biosynthesis inhibitor. (Rac)-Brassinazole increases inhibition of CYP90B in BR biosynthesis[1][2]

Name	4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazol-1-yl)butan-2-ol
Synonyms	4-(4-Chlorophenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)butan-2-ol 3-(4-Chlorophenyl)-1-methyl-1-phenyl-2-(1,2,4-triazol-1-yl)-1-propanol 4-(4-Chlorophenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)-2-butanol Brassinazole 1H-1,2,4-Triazole-1-ethanol, β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl- 1-[2-(4-Chlorophenyl)-1-(1-hydroxy-1-phenylethyl)ethyl]-1,2,4-triazole 4-(4-chlorophenyl)-2-phenyl-3-(1,2,4-triazol-1-yl)butan-2-ol

Description	(Rac)-Brassinazole, triazole-type compound, is a brassinosteroid (BR) biosynthesis inhibitor. (Rac)-Brassinazole increases inhibition of CYP90B in BR biosynthesis[1][2]
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Metabolic Disease
In Vitro	(Rac)-Brassinazole (compound 5) does not retard rice stem elongation, and retardation is recovered by the addition of gibberellin (GA3), suggesting that such retardation is due to the inhibition of gibberellin biosynthesis[1]. (Rac)-Brassinazol (compound 31) results in a reduction in the effect on AtKO in gibberellin (GA) biosynthesis[2].
References	[1]. Y K Min, et al. New Lead Compounds for Brassinosteroid Biosynthesis Inhibitors. Bioorg Med Chem Lett. 1999 Feb 8;9(3):425-30. [2]. Eriko Sasaki, et al. Uniconazole, a Cytochrome P450 Inhibitor, Inhibits Trans-Zeatin Biosynthesis in Arabidopsis. Phytochemistry. 2013 Mar;87:30-8.

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