934282-55-0

934282-55-0 structure

Name: AZD 2066
Chemical Name: 5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2-oxazole
CAS Number: 934282-55-0
Molecular Formula: C₁₉H₁₆ClN₅O₂
Molecular Weight: 381.81600
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2017-08-10 09:02:15
Modify Date: 2024-01-23 21:11:31
AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].

Name	5-(3-chlorophenyl)-3-[(1R)-1-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)oxy]ethyl]-1,2-oxazole
Synonyms	unii-mq908y1zb2 azd2066

Description	AZD 2066 is a selective, orally active and brain-penetrant mGluR5 antagonist, with analgesia activity[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
References	[1]. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22.