29706-84-1
29706-84-1 structure
- Name: 5'-O-Trt-Zidovudine
- Chemical Name: 1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
- CAS Number: 29706-84-1
- Molecular Formula: C29H27N5O4
- Molecular Weight: 509.56
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2016-12-05 11:57:46
- Modify Date: 2024-01-10 18:00:19
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3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| Synonyms |
3-Azido-3-deoxy-5-O-triphenylmethylthymidine
3'-Azido-3'-deoxy-5'-O-tritylthymidine Thymidine,3'-azido-3'-deoxy-5'-O-trityl-(8CI) Thymidine,3'-azido-3'-deoxy-5'-O-(triphenylmethyl) 5'-O-Trt-Zidovudine |
| Description | 3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Melting Point | 103-104 °C(Solv: toluene (108-88-3)) |
|---|---|
| Molecular Formula | C29H27N5O4 |
| Molecular Weight | 509.56 |
| Exact Mass | 509.20600 |
| PSA | 123.33000 |
| LogP | 4.68516 |
| Storage condition | 2-8℃ |
| Precursor 0 | |
|---|---|
| DownStream 4 | |
![1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-4-(methylamino)pyrimidin-2-one structure](https://www.chemsrc.com/caspic/492/108895-46-1.png)
