170569-87-6

170569-87-6 structure

Name: Desmethyl Celecoxib
Chemical Name: 4-[5-(phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
CAS Number: 170569-87-6
Molecular Formula: C₁₆H₁₂F₃N₃O₂S
Molecular Weight: 367.346
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2016-11-12 14:16:54
Modify Date: 2025-09-04 11:46:22
Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1].

Name	4-[5-(phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Synonyms	4-[5-phenyl-3-trifluoromethyl-1H-pyrazol-1-yl]benzene-sulfonamide 4-[5-phenyl-3-(trifluoromethyl) -1H-pyrazol-1-yl] benzenesulfonamide 4-[5-Phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide Benzenesulfonamide, 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]- 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide 1-(4-sulfonamidophenyl)-5-phenyl-3-(trifluoromethyl)-1H-pyrazole Desmethyl Celecoxib 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1yl]benzenesulfonamide 1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE

Description	Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2:32 nM (IC50)
References	[1]. Vinay Kumar Sthalam, et al. An Integrated Continuous Flow Micro-Total Ultrafast Process System (μ-TUFPS) for the Synthesis of Celecoxib and Other Cyclooxygenase Inhibitors. RETURN TO ISSUEPREVARTICLENEXT

Hazard Codes	Xi