150403-97-7

150403-97-7 structure

Name: ETHYL-L-NIO (HYDROCHLORIDE)
Chemical Name: chloro (2S)-2-amino-5-(1-aminobutylideneamino)pentanoate
CAS Number: 150403-97-7
Molecular Formula: C₉H₁₈ClN₃O₂
Molecular Weight: 235.71100
Catalog: Research Areas Others
Create Date: 2016-03-03 01:38:58
Modify Date: 2024-04-09 09:20:15
Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM[1].

Name	chloro (2S)-2-amino-5-(1-aminobutylideneamino)pentanoate
Synonyms	Ethyl-L-NIO,hydrochloride

Description	Ethyl-L-NIO hydrochloride is a potent and competitive human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1) inhibitor with an IC50 of 70 μM and a Ki of 32 μM[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	IC50: 70 μM (hDDAH-1)[1] Ki: 32 μM (hDDAH-1)[1]
References	[1]. Kotthaus J, et al. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads. Bioorg Med Chem. 2008 Dec 15;16(24):10205-9.