Zhejiang Hangyu API Co., Ltd
China
Product Name: Head activator
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

79943-68-3

79943-68-3 structure

79943-68-3 structure

Name: Head activator
Chemical Name: head activator neuropeptide
CAS Number: 79943-68-3
Molecular Formula: C₅₄H₈₄N₁₂O₁₄
Molecular Weight: 1125.32000
Catalog: Research Areas Cancer
Create Date: 2016-09-17 14:15:01
Modify Date: 2024-01-06 19:30:19
Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1].

Name	head activator neuropeptide

Description	Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	GPR37[1]
In Vitro	Head activator neuropeptide (2 nM，0-60 分钟) 在转染了 GPR37-FLAG 的 COS-7 细胞中刺激 GPR37 的内化[1]。 Head activator neuropeptide (EC50: 3.3 nM) 增加转染载脂蛋白和 GPR37[1] 的 CHO-K1 细胞中的 Ca2+ mobilisation[1]。 Head activator neuropeptide (EC50: 5.6 nM) 刺激表达 GPR37 的青蛙卵母细胞的电流增加[1]。
References	[1]. Rezgaoui M, et al. The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37. J Cell Sci. 2006 Feb 1;119(Pt 3):542-9.

Density	1.271g/cm3
Boiling Point	1506.5ºC at 760 mmHg
Molecular Formula	C₅₄H₈₄N₁₂O₁₄
Molecular Weight	1125.32000
Flash Point	864.9ºC
Exact Mass	1124.62000
PSA	386.07000
LogP	1.61710
Index of Refraction	1.564

WGK Germany	3