Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Magnoflorine iodide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

4277-43-4

4277-43-4 structure

Name: Magnoflorine Iodide
Chemical Name: (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol,iodide
CAS Number: 4277-43-4
Molecular Formula: C₂₀H₂₄INO₄
Molecular Weight: 469.31300
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-05-08 08:00:00
Modify Date: 2025-08-20 11:25:35
(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm[1]. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].

Name	(6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol,iodide
Synonyms	Corytuberine Methiodide Magnoflorine Iodide (6CI,7CI) Thalictrine Iodide Escholine Iodide Magnoflorin-iodid magnoflorine Magnoflorine,iodide Magnoflorine iodide

Description	(+)-Magnoflorine iodide (Magnoflorine iodide), an aporphine alkaloid found in Acoruscalamus, reduces the formation of C. albicans biofilm[1]. (+)-Magnoflorine iodide has anti-fungal, anti-antidiabetic and anti-oxidative activity[2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Metabolic Disease
References	[1]. Kim J, et al. Antifungal activity of magnoflorine against Candida strains. World J Microbiol Biotechnol. 2018 Oct 31;34(11):167. [2]. Haque MA, et al. Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages. Planta Med. 2018 Nov;84(17):1255-1264.

Melting Point	248-249ºC
Molecular Formula	C₂₀H₂₄INO₄
Molecular Weight	469.31300
Exact Mass	469.07500
PSA	58.92000
Storage condition	2-8C

517-56-6

74-88-4

~86%

4277-43-4

Literature: Slavik, Jiri; Slavikova, Leonora Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 7 p. 2009 - 2020

6681-18-1

4277-43-4

Literature: Pachaly; Schneider Archiv der Pharmazie, 1981 , vol. 314, # 3 p. 251 - 256

74-88-4

4277-43-4

Literature: Nakano Pharmaceutical Bulletin, 1954 , vol. 2, p. 329 Full Text View citing articles Show Details Pailer; Pruckmaier Monatshefte fuer Chemie, 1959 , vol. 90, p. 145,147

Precursor 3
517-56-6 74-88-4 6681-18-1
DownStream 0

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