101932-71-2
101932-71-2 structure
- Name: Calyculin A
- Chemical Name: Calyculin A from Discodermia calyx
- CAS Number: 101932-71-2
- Molecular Formula: C50H81N4O15P
- Molecular Weight: 1009.17000
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphatase
- Create Date: 2018-06-28 10:40:23
- Modify Date: 2025-08-27 16:02:55
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Calyculin A is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.5 to 1 nM.
| Name | Calyculin A from Discodermia calyx |
|---|---|
| Synonyms |
Calyculin A,N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-o
MFCD00133156 Calyculin A |
| Description | Calyculin A is a potent and cell-permeable protein phosphatase 1 (PP1) and protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.5 to 1 nM. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.25g/cm3 |
|---|---|
| Molecular Formula | C50H81N4O15P |
| Molecular Weight | 1009.17000 |
| Exact Mass | 1008.54000 |
| PSA | 296.80000 |
| LogP | 5.07988 |
| Index of Refraction | 1.57 |
| Storage condition | 2-8℃ |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 + H311 + H331-H315 |
| Precautionary Statements | P261-P280-P301 + P310-P311 |
| Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | T: Toxic; |
| Risk Phrases | 23/24/25-38 |
| Safety Phrases | 36/37/39-45 |
| RIDADR | UN 3462 6.1/PG 3 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |