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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: 1-(2-Hydroxyethyl)-2-pyrrolidinone
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Henan Tianfu Chemical Co., Ltd.
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Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: 1-(2-Hydroxyethyl)-2-pyrrolidinone
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3445-11-2

3445-11-2 structure

Name: 1-(2-Hydroxyethyl)-2-pyrrolidinone
Chemical Name: 1-(2-hydroxyethyl)pyrrolidin-2-one
CAS Number: 3445-11-2
Molecular Formula: C₆H₁₁NO₂
Molecular Weight: 129.157
Create Date: 2018-03-12 08:00:00
Modify Date: 2025-08-25 20:08:41

Name	1-(2-hydroxyethyl)pyrrolidin-2-one
Synonyms	N-(2-Hydroxyethyl)-2-pyrrolidone 1-(2-Hydroxyethyl)-2-Pyrrolidone 1-(2-hydroxyethyl)pyrrolidin-2-one N-(2-hydroxyethyl)-2-oxo-pyrrolidine EINECS 222-359-4 N-(2-hydroxyethyl)-pyrrolidinone N-2-Hydroxyethylpyrrolidin-2-one N-(2-hydroxyethyl)-2-pyrrolidinone 1-(2-Hydroxyethyl)-2-pyrrolidinone 2-Pyrrolidinone,1-(2-hydroxyethyl) 2-Pyrrolidinone, 1-(2-hydroxyethyl)- MFCD00014103

Density	1.2±0.1 g/cm3
Boiling Point	296.0±13.0 °C at 760 mmHg
Melting Point	19-21°C
Molecular Formula	C₆H₁₁NO₂
Molecular Weight	129.157
Flash Point	132.8±19.8 °C
Exact Mass	129.078979
PSA	40.54000
LogP	-1.02
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.505
Stability	Stable. Incompatible with strong oxidizing agents

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UY5776500

CHEMICAL NAME :: 2-Pyrrolidinone, 1-(2-hydroxyethyl)-

CAS REGISTRY NUMBER :: 3445-11-2

BEILSTEIN REFERENCE NO. :: 0112181

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H11-N-O2

MOLECULAR WEIGHT :: 129.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0448S ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0682-0448S

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	UY5776500
HS Code	2933790090

59776-88-4

~86%

3445-11-2

Literature: Ito, Masato; Ootsuka, Takashi; Watari, Ryo; Shiibashi, Akira; Himizu, Akio; Ikariya, Takao Journal of the American Chemical Society, 2011 , vol. 133, # 12 p. 4240 - 4242

96-48-0

141-43-5

~87%

3445-11-2

Literature: Lisina, N. I.; Chernov, G. A.; Bizunov, Yu. M.; Emel'yanov, V. I.; Knunyants, I. L. Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 6 p. 472 - 476 Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 6 p. 705 - 710

13865-19-5

141-43-5

3445-11-2

Literature: US4420620 A1, ;

66857-17-8

3445-11-2

Literature: Justus Liebigs Annalen der Chemie, , vol. 596, p. 1,201

51333-90-5

3445-11-2

Literature: Tetrahedron, , vol. 45, # 19 p. 6161 - 6170

75-21-8

123-75-1

3445-11-2

Literature: Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 111; engl. Ausg. S. 109

75-21-8

616-45-5

3445-11-2

Literature: Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 111; engl. Ausg. S. 109

Precursor 9
59776-88-4 96-48-0 141-43-5 13865-19-5
66857-17-8 51333-90-5 75-21-8 123-75-1
616-45-5
DownStream 10
51333-90-5 616-45-5 2687-91-4 88-12-0
75-07-0 7491-74-9 117018-99-2 7663-76-5
863442-96-0 86366-53-2

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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