Name | 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol,phosphoric acid,hydrate |
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Synonyms |
2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-, phosphate, hydrate (2:2:1) (salt)
Carvedilol phosphate hydrate (JAN) Carvedilol phosphate hemihydrate Coreg CR (TN) 1-(9H-Carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}-2-propanol phosphate hydrate (2:2:1) Carvedilol phosphate Carvedilol (phosphate hemihydrate) |
Description | Carvedilol is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.IC50 Value: 3.8 μM ( inhibition of LDL oxidation)Target: beta Adrenergic ReceptorCarvedilol is a nonselective-blocking agent and is used in the treatment of hypertension and angina pectoris. As a third-generation β-adrenergic blocker (β-blocker), Carvedilol is able to reverse cardiac structural remodeling. Recentresults demonstrated that the effect caused by Carvedilol on cardiac remodeling is largely dependent on endogenous NO. |
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Related Catalog | |
References |
[2]. Stafylas PC, et al. Carvedilol in hypertension treatment. Vasc Health Risk Manag. 2008;4(1):23-30. |
Boiling Point | 655.2ºC at 760 mmHg |
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Molecular Formula | C24H26N2O4.H3PO4.1/2H2O |
Molecular Weight | 513.48 |
Flash Point | 350.1ºC |
PSA | 172.54000 |
LogP | 3.13600 |
Storage condition | -20℃ |