549-92-8

549-92-8 structure

Name: Sempervirine
Chemical Name: sempervirine nitrate
CAS Number: 549-92-8
Molecular Formula: C₁₉H₁₆N₂
Molecular Weight: 331.32500
Catalog: Natural product Alkaloid
Create Date: 2018-06-01 08:00:00
Modify Date: 2025-08-30 04:28:38
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

Name	sempervirine nitrate
Synonyms	sempervirine yohimba-2,5,14,20-tetraene Sempervirin

Description	Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume

Risk Phrases	23/24/25
Safety Phrases	22-36/37/39