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549-92-8

549-92-8 structure
549-92-8 structure
  • Name: Sempervirine
  • Chemical Name: sempervirine nitrate
  • CAS Number: 549-92-8
  • Molecular Formula: C19H16N2
  • Molecular Weight: 331.32500
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-06-01 08:00:00
  • Modify Date: 2024-01-10 14:50:34
  • Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].

Name sempervirine nitrate
Synonyms sempervirine
yohimba-2,5,14,20-tetraene
Sempervirin
Description Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2].
Related Catalog
References

[1]. Noriyuki Kogure, et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines volume 

Density 1.28g/cm3
Boiling Point 591.6ºC at 760mmHg
Melting Point 271ºC
Molecular Formula C19H16N2
Molecular Weight 331.32500
Flash Point 311.6ºC
Exact Mass 331.09600
PSA 88.77000
LogP 4.49710
Risk Phrases 23/24/25
Safety Phrases 22-36/37/39