| Name | Oxybis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) |
|---|---|
| Synonyms |
Ethanol, 2,2'-oxybis-, bis(4-methylbenzenesulfonate)
Oxydi-2,1-ethanediyl bis(4-methylbenzenesulfonate) oxydiethane-2,1-diyl bis(4-methylbenzenesulfonate) MFCD00026001 2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethyl 4-methylbenzenesulfonate |
| Description | Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 581.2±45.0 °C at 760 mmHg |
| Melting Point | 87-89 °C(lit.) |
| Molecular Formula | C18H22O7S2 |
| Molecular Weight | 414.493 |
| Flash Point | 305.3±28.7 °C |
| Exact Mass | 414.080688 |
| PSA | 112.73000 |
| LogP | 2.70 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.554 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2904100000 |
| HS Code | 2904100000 |
|---|---|
| Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |