CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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PA8750000
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CHEMICAL NAME :
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Methane, dimethoxy-
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CAS REGISTRY NUMBER :
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109-87-5
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LAST UPDATED :
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199712
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DATA ITEMS CITED :
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35
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MOLECULAR FORMULA :
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C3-H8-O2
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MOLECULAR WEIGHT :
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76.11
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WISWESSER LINE NOTATION :
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1O1O1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536049 ** ACUTE TOXICITY DATA **
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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15000 ppm
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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NPIRI* Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. (National Assoc. of Printing Ink Research Institute, Francis McDonald Sinclair Memorial Laboratory, Lehigh Univ., Bethlehem, PA 18015) Volume(issue)/page/year: 1,73,1974
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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5 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0524346
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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57 gm/m3/7H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,259,1986
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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5708 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 29,730,1932
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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>16 mL/kg
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - iritis Lungs, Thorax, or Respiration - other changes Liver - other changes
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536049 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TCLo - Lowest published toxic concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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35100 mg/m3/7H/22D-I
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REFERENCE :
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BJIMAG British Journal of Industrial Medicine. (British Medical Journal, Box 560B, Kennebunkport, ME 04046) V.1- 1944- Volume(issue)/page/year: 8,279,1951 *** REVIEWS *** ACGIH TLV-TWA 3110 mg/m3 (1000 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1000 ppm (3100 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,154,1971 OSHA PEL (Gen Indu):8H TWA 1000 ppm (3100 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 1000 ppm (3100 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 1000 ppm (3100 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 1000 ppm (3100 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-BELGIUM:TWA 1000 ppm (3110 mg/m3) JAN 1993 OEL-DENMARK:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-FINLAND:TWA 1000 ppm (3100 mg/m3);STEL 1250 ppm (3900 mg/m3) JAN 1993 OEL-FRANCE:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-GERMANY:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-POLAND:TWA 1000 mg/m3 JAN 1993 OEL-RUSSIA:STEL 10 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-TURKEY:TWA 1000 ppm (3100 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 1000 ppm (3100 mg/m3);STEL 1250 ppm JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO METHYLAL-air:10H TWA 1000 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 26075 No. of Facilities: 122 (estimated) No. of Industries: 5 No. of Occupations: 6 No. of Employees: 399 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 26075 No. of Facilities: 9104 (estimated) No. of Industries: 123 No. of Occupations: 70 No. of Employees: 156806 (estimated) No. of Female Employees: 21093 (estimated)
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