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53696-74-5

53696-74-5 structure
53696-74-5 structure
  • Name: Armillarisin A
  • Chemical Name: 3-Acetyl-7-hydroxy-5-(hydroxymethyl)-2H-chromen-2-one
  • CAS Number: 53696-74-5
  • Molecular Formula: C12H10O5
  • Molecular Weight: 234.205
  • Catalog: API Digestive system medication Biliary medicine
  • Create Date: 2018-03-09 08:00:00
  • Modify Date: 2024-01-09 23:44:48
  • Armillarisin A has the potential for the ulcerative colitis (UC) study. Armillarisin A increases IL-4 and lower IL-1β[1].

Name 3-Acetyl-7-hydroxy-5-(hydroxymethyl)-2H-chromen-2-one
Synonyms 3-Acetyl-5-hydroxylmethyl-7-hydroxycoumarin
2H-1-Benzopyran-2-one, 3-acetyl-7-hydroxy-5-(hydroxymethyl)-
MFCD01662561
3-acetyl-7-hydroxy-5-(hydroxymethyl)chromen-2-one
3-Acetyl-7-hydroxy-5-(hydroxymethyl)-2H-chromen-2-one
Armillarisin A
Description Armillarisin A has the potential for the ulcerative colitis (UC) study. Armillarisin A increases IL-4 and lower IL-1β[1].
Related Catalog
References

[1]. Ping Wu, et al. The Effects of Armillarisin A on Serum IL-1β and IL-4 and in Treating Ulcerative Colitis. Cell Biochem Biophys. 2015 May;72(1):103-6.

Density 1.5±0.1 g/cm3
Boiling Point 565.0±50.0 °C at 760 mmHg
Melting Point 250-255ºC
Molecular Formula C12H10O5
Molecular Weight 234.205
Flash Point 227.2±23.6 °C
Exact Mass 234.052826
PSA 87.74000
LogP 0.13
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.642

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ2976500
CHEMICAL NAME :
2H-1-Benzopyran-2-one, 3-acetyl-7-hydroxy-5-(hydroxymethyl)-
CAS REGISTRY NUMBER :
53696-74-5
LAST UPDATED :
199707
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H10-O5
MOLECULAR WEIGHT :
234.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 16,401,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
YHHPAL Yaoxue Xuebao. Acta Pharmaceutica Sinica. Pharmaceutical Journal. (China International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 1953- Suspended 1966-78. Volume(issue)/page/year: 16,401,1981
HS Code 2932209090
HS Code 2932209090
Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%