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1391063-17-4

1391063-17-4 structure
1391063-17-4 structure
  • Name: PF-06651481-00
  • Chemical Name: bosutinib-I
  • CAS Number: 1391063-17-4
  • Molecular Formula: C26H29Cl2N5O3
  • Molecular Weight: 530.45
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Wee1
  • Create Date: 2016-12-17 16:25:10
  • Modify Date: 2024-01-10 00:00:27
  • Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].

Name bosutinib-I
Synonyms Bosutinib Isomer 1
bosutinib
Description Bosutinib isomer is a ligand or inhibitor with high binding affinity for both Wee1 and Wee2, with Kd values of 43.7 ± 10.0 and 4.7 ± 2.3 nM, respectively[1].
Related Catalog
References

[1]. Zhu JY, et al. Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J Med Chem. 2017 Sep 28;60(18):7863-7875.  

Molecular Formula C26H29Cl2N5O3
Molecular Weight 530.45
Exact Mass 529.16500
PSA 82.88000
LogP 5.13918
RIDADR NONH for all modes of transport