61012-19-9

61012-19-9 structure

Name: (Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH trifluoroacetate salt
Chemical Name: lecirelin
CAS Number: 61012-19-9
Molecular Formula: C₅₉H₈₄N₁₆O₁₂
Molecular Weight: 1209.398
Catalog: Peptides
Create Date: 2018-08-13 00:04:25
Modify Date: 2024-01-08 16:56:31
Lecirelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue. Lecirelin is widely used for the research of bovine ovarian follicular cysts[1].

Name	lecirelin
Synonyms	Lecirelin (Dalmarelin) Acetate 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-methyl-D-valyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-methyl-D-valyl-L-leucyl-L-arginyl-N-ethyl- Lecirelin Acetate Supergestran GLP-HIS-TRP-SER-TYR-TLE-LEU-ARG-PRO-NHET

Description	Lecirelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue. Lecirelin is widely used for the research of bovine ovarian follicular cysts[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> GNRH Receptor Research Areas >> Cancer Research Areas >> Endocrinology
In Vitro	Lecirelin (2.07 μM) significantly increases the tension and frequency of contractions in preovulatory follicles (PF), small follicular cysts (FC-S), and large follicular cysts (FC-L)[1]. Lecirelin increases the strips from preovulatory follicles contract significantly more than strips from cysts[1].
References	[1]. Rizzo A et al. Bovine ovarian follicular cysts: in vitro effects of lecirelin, a GnRH analogue. Theriogenology. 2010 Dec;74(9):1559-69.