137018-54-3

137018-54-3 structure

Name: Okicenone
Chemical Name: 4,6,9-trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one
CAS Number: 137018-54-3
Molecular Formula: C₁₅H₁₄O₄
Molecular Weight: 258.26900
Catalog: Research Areas Inflammation/Immunology
Create Date: 2016-10-05 07:23:35
Modify Date: 2025-08-25 10:02:29
Okicenone is a Hu protein R (HuR) inhibitor. Okicenone inhibits HuR oligomerization, interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation[1].

Name	4,6,9-trihydroxy-8-methyl-3,4-dihydro-2H-anthracen-1-one
Synonyms	Okicenone 1(2H)-Anthracenone,3,4-dihydro-4,6,9-trihydroxy-8-methyl 3,4-Dihydro-4,6,9-trihydroxy-8-methyl-1(2H)-anthracenone

Description	Okicenone is a Hu protein R (HuR) inhibitor. Okicenone inhibits HuR oligomerization, interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Meisner NC, et al. Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol. 2007 Aug;3(8):508-15.