62030-88-0
62030-88-0 structure
- Name: Duoperone
- Chemical Name: (4-fluorophenyl)-[1-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperidin-4-yl]methanone
- CAS Number: 62030-88-0
- Molecular Formula: C28H26F4N2OS
- Molecular Weight: 514.57700
- Catalog: Research Areas Neurological Disease
- Create Date: 2017-03-09 12:58:09
- Modify Date: 2025-09-18 16:59:12
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Duoperone is a neuroleptic agent and also a antiemetic agent in animal models.
| Name | (4-fluorophenyl)-[1-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperidin-4-yl]methanone |
|---|---|
| Synonyms |
Duoperonum [Latin]
DUOPERONE FUMARATE (4-fluoro-phenyl)-{1-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperidin-4-yl}-methanone Duoperona 2-trifluoromethyl-10-{3-[4-(p-fluorobenzoyl)piperidinyl]propyl}phenothiazine UNII-E84FJ4KW3B Duoperone Duoperona [Spanish] Duoperonum Duoperone [INN] Duoperone fumarate [USAN] |
| Description | Duoperone is a neuroleptic agent and also a antiemetic agent in animal models. |
|---|---|
| Related Catalog | |
| In Vivo | Duoperone blocks d-amphetamine lethality in mice under aggregated conditions when the pretreatment interval is between one hour and seven days. ABR-6646 produces catalepsy in rats. The onset of this effect is delayed and the duration is prolonged when compared with that of chlorpromazine. Apomorphine-induced pivoting in mice with unilateral lesions of the caudate nucleus is suppressed by ARR-6646[1]. |
| References |
| Density | 1.289g/cm3 |
|---|---|
| Boiling Point | 613.5ºC at 760 mmHg |
| Molecular Formula | C28H26F4N2OS |
| Molecular Weight | 514.57700 |
| Flash Point | 324.8ºC |
| Exact Mass | 514.17000 |
| PSA | 48.85000 |
| LogP | 7.43510 |
| Index of Refraction | 1.587 |
| Storage condition | 2-8℃ |
|
~%
62030-88-0 |
| Literature: Boswell Jr.; Welstead Jr.; Duncan Jr.; Johnson; Funderburk Journal of medicinal chemistry, 1978 , vol. 21, # 1 p. 136 - 139 |
