DC Chemicals Limited
China
Product Name: Loperamide oxide
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Loperamide
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

106900-12-3

106900-12-3 structure

106900-12-3 structure

Name: Loperamide
Chemical Name: 4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
CAS Number: 106900-12-3
Molecular Formula: C₂₉H₃₃ClN₂O₃
Molecular Weight: 493.03700
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2018-03-31 08:00:00
Modify Date: 2024-01-02 20:14:52
Loperamide oxide is a prodrug of the effective antidiarrheal loperamide.

Name	4-[4-(4-chlorophenyl)-4-hydroxy-1-oxidopiperidin-1-ium-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide
Synonyms	Loperamide N-oxide Loperamide oxide trans-N-Oxide of loperamide Arestal

Molecular Formula	C₂₉H₃₃ClN₂O₃
Molecular Weight	493.03700
Exact Mass	492.21800
PSA	69.97000
LogP	5.05940
Water Solubility	Practically insoluble in water, freely soluble in alcohol and in methylene chloride.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM4960200

CHEMICAL NAME :: 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha -diphenyl-, 1-oxide, (E)-

CAS REGISTRY NUMBER :: 106900-12-3

LAST UPDATED :: 198910

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C29-H33-Cl-N2-O3

MOLECULAR WEIGHT :: 493.09

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 172 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 8,279,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 8,279,1986

RIDADR	UN 2811 6.1 / PGIII
RTECS	TM4960200